Review Medicine Use

Clomid

Clomid is used in conventional medicine, as a rule, to stimulate ovulation. Clomid stimulates the release of gonadotropins through the release of certain hormones.
Also it restores ovulatory cycle in women. Nevertheless the drug is intended for women, its effect is manifested to men, as Clomid gives a profound effect on the reflex arc "hypothalamus-pituitary-testes."

It stimulates the pituitary gland to release more gonadotropin, which leads to a rapid increase in the number of follicle stimulating and luteinizing hormones in the blood. The result increases the levels of endogenous testosterone. Clomid works, above all, when the result of taking anabolic-androgenic steroids, is suppressed by its own production of testosterone.
In most cases Clomid normalizes the levels of testosterone and spermatogenesis in 10-14 days. Therefore, it is accepted as the cessation of steroid use. At this time, it is extremely important to restore testosterone production as quickly as possible to minimize the loss of strength and muscle massy. Such great results are achieved when combined with Clomid chorionic gonadotrophin (HCG), or when Clomid is taken after treatment with HCG.
The difference between Clomid and HGT is that Clomid has a direct effect on the hypothalamus and pituitary gland and triggers the entire reflex arc, while HCG increases the impact of luteinizing hormone, which in turn stimulates the cells of the testes to a greater production of testosterone. Since the HGT in contrast to Clomid had a few hours after taking it significantly increases the level of testosterone, many athletes take the first HGT and after Clomid.

Although Clomid is a synthetic estrogen, it acts, paradoxically, as an antiestrogen. It blocks the stronger estrogens, resulting in aromatization. This, of course, does not prevents the aromatization of steroids, but multiplied estrogens are still largely inactivated. Severe water retention and possible feminization can be sealed or completely eliminated.
Since the Clomid is in its anti-estrogenic effects of Nolvadex and Proviron weaker, it is mainly used as a stimulant for testosterone production.
Adverse events at reasonable doses are very rare. Possible events – climax of sweat, in some cases – visual disturbances, which are expressed in vague images or in circles before my eyes. When violations of the drug manufacturers are advised to permanently discontinue Clomid, hepatic dysfunction is not excluded, but unlikely. Women may have the phenomenon of increasing ovarian pain in the abdomen, as Clomid stimulates the ovaries. It increases the possibility of pregnancy.
With regard to dosage, it is usually enough to 50-100 mg per day (1-2 tablets). The tablets are usually taken after meals with a glass of liquid. When you receive a larger number of pills recommended daily dose divided into equal multiple techniques. The duration of intake should not exceed 10-14 days. Most athletes begin with 100 mg per day, taking them to 50 mg in the morning and evening after meals. On the fifth day of taking the dose is often reduced to one 50 mg tablet per day.
No need to take medication more than 10-14 days to raise the level of endogenous testosterone. Since the Clomid should not be used for a longer time, its use as an anti-estrogen disappears by itself, because to this end it should be applied over several weeks.

Dosage and administration:

To stimulate ovulation appoint 50 mg 1  once daily at bedtime, starting with 5 days of the menstrual cycle, for 5 days (in the absence of the cycle – at any time). If there is no effect (ovulation does not develop within 30 days) to increase the dose to 150 mg / day or lengthen the course of 10 days. Heading dose should not exceed 1 g. Development of ovulation is determined by the presence of biphasic basal body temperature, the average cyclical increase production of LH, serum progesterone rise during the luteal phase of the likely average or menstruation of women with amenorrhea. If ovulation occurs and pregnancy is not, then repeat the reception of the same dose the next cure. If, after ovulation took place probably did not follow her menstrual bleeding, should take into account the possibility of pregnancy, and before a new course of treatment that possibility should be excluded. Men assigned to 50 mg 1-2 times daily for 3-4 months (requires systematic monitoring spermatogram).

The main feature of Clomid is that it is not only struggling with excess of estradiol in the blood by blocking the receptors of this hormone, but also helps to restore the level of luteinizing hormone (LH) in men. A N – is a key element in the production of the male body’s own testosterone.

Another interesting feature of Clomid – under certain conditions it is not a blocker and an activator of estrogen receptors, it all depends on whether joined together with Clomid for a specific estrogen receptor cofactor. Type of co-factor depends on the type Tacna, in other words, in some tissues (hypothalamus, breast cancer) Clomid acts as an estrogen receptor blocker, which is even desirable, in others (bone), as an activator of the same receptor, which is not a bad idea, because helps prevent osteoporosis.
Clomid can be used throughout the steroid "cycle", but basically this drug is used at the end of the steroid.

Cautions:
Clomid can not be assigned without doctor’s advice to persons whose professional activity requires quick physical and mental reactions. With an increase in ovarian or cystic transformation, the treatment clomiphene suspended until the normalization of the size of the ovaries. Continue therapy with low doses or shorten the treatment period. The treatment is recommended to monitor liver function.

Indications for use Clomid:

Anovulatory infertility, dysfunctional uterine bleeding, amenorrhea, galactorrhea (compared to a pituitary tumor), polycystic ovarian syndrome (Stein – Leventhal) syndrome, Chiari – Frommelya, androgen deficiency, oligospermia, for the diagnosis of pituitary gonadotrophic function.